Susan,It depends on how advanced you want to go. If your operating an online or mail/ phone order business you can use a system known as quickbooks that will also allow you to do inventory control, accept credit cards and most anything else. If your new to the business, it is retail based, or just want the basics you can create your own spreadsheet and use it.Computers are making things much easier for business owners to keep track of inventory, contacts, payroll and a multitude of things that help in general.
In addition to the last answer - Excel Spreadsheets are quite useful.They have features whereby, the sheet automatically update s itself.Best Wishes