Look each one in the eye to acknowledge their presence smile and tell them something like you will help them as soon as possible; the apologize for the wait when serving them and thank them for their patience ( i work at Macys)
Work together at the cash by having one of you prepare the clothes for easy scanning and the other taking the payments. Apologize for the wait and thank them for coming.
do the best you can and apologize for the inconvenience.