No, you don t need any college credits at all to obtain a business license. A business license is just for taxation purposes. However, in order to have a better shot at succeeding in your business, you should either take some classes (like Accounting, Management, Human Resources, etc.) or have access to a team of people knowledgeable in those areas. You will also need an accountant, an attorney, an insurance agent, and a banker.Check with your local SCORE office and/or local Small Business Administration office for further information.
Anybody can get a business license even if you don t have an education. Talk to your local chamber of commerce regarding what steps you need to take to get it since different municipalities have different requirements (fees, locations, etc.). They are a great source for not only getting a license but helping actually establish the business and keep it running efficiently.
A business license doesn t require anything but money. However, business courses would be very valuable.